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New study finds effect of aging on gut microbes

A new study shows that aging leads to a significant change in the human gut microbiome.

A new American study found that aging leads to significant changes in the microbiome of the human small intestine, differently from those caused by taking medications or contracting various diseases, according to the Asian International News Agency (ANI).

And the agency quoted, in a report published on Saturday, the study’s lead author, Dr. Ruchi Mathur, as saying: “By knowing the microbial changes that occur in the small intestine with age, and separating them from those that occur due to drug use or disease, we hope to identify the components of unique to this microbial community to target therapies and interventions that can promote health in old age.”

According to Mathur, the study that explored the gut microbiome, and its impact on health, relied mostly on stool samples. Samples from the small intestine, more than 20 feet in length, to examine the microbiome and its relationship to aging.

Mathur adds: “This study is the first of its kind to examine the microbial composition of the small intestine in people aged 18-80 years. It is only affected by a person’s age.”

The agency pointed out that the twenty-first century has always been described as the “age of the gut microbiome” where scientists pay great attention to the role that trillions of bacteria, fungi and viruses may play in human health or disease, as many studies indicate that disruptions in these microbes may lead It leads to serious diseases, including gastrointestinal diseases, diabetes, obesity, and some neurological disorders.

She continued, “It is known to researchers that microbial diversity in stool decreases with age, but Cedars-Sinai researchers were able to identify bacteria in the small intestine they describe as ‘inactivated’, which they say increases with age and may have a disturbing effect.”

“We found that when the number of coliforms in the small intestine increases, which happens with age, it has a negative effect on the rest of the microbes,” says study co-author Gabriella Leite.

The researchers also found that as people age, bacteria in the small intestine switch from one that prefers oxygen to one that can survive with less oxygen, something they hope to understand as research continues.

The agency also quoted study co-author Mark Pimentel as saying: “Our goal is to identify microbial patterns in the small intestine during human health and disease. From the gut may have a greater impact on human health, which warrants further study.”