There is no doubt that the decline in the effectiveness of the anti-Corona vaccines after a period of time has become scientifically proven, although the “timing” is still a matter of controversy and research at the same time.
With millions around the world wondering when the booster dose should be taken, a new Australian study shows that a third dose may be needed within one year to keep the vaccine’s efficacy above 50 percent.
This result, which was published in the latest issue of “The Lancet Microbe”, according to what was reported by the Middle East newspaper, came after an analysis conducted by researchers from the Sydney Institute of Infectious Diseases at the University of Sydney, the Kirby Institute at the University of New South Wales, in addition to the Dorty Institute at the University of Melbourne. It is the largest of its kind, for predicting the efficacy of vaccines with variants using neutralizing antibodies.
Predicting the efficacy of a vaccine
In the context, Jamie Tricas of the University of Sydney, and one of the study’s authors, said in a report published on the University of Sydney website, a few days ago, that “this research is important because it shows that we can predict the effectiveness of the vaccine through a relatively simple laboratory test.”
He also added: “It is possible that new virus variants will continue to emerge, as we saw with Delta, with varying transmissibility and severity, and vaccines may not work well against some of those variants, but fortunately, our model allows for that prediction.”
By analyzing existing data on the effectiveness of neutralizing antibody responses in infected and vaccinated individuals against different viral variants, the researchers participating in this study found that antibodies induced by infection or vaccination were less protective against variants of concern, and that over time, there was a reduction in in antibodies.
They also concluded that these changes could be used to predict the effectiveness of a vaccine.
It is noteworthy that the vaccines work well during the first months after vaccination, but this study showed a decrease in the effectiveness of the vaccine against “Covid-19”, resulting from variables such as delta and others, which over time reduced the effectiveness of the vaccine.
The analysis was able to proactively predict this decrease based on analysis of antibody levels.
It is noteworthy that the World Health Organization stated yesterday, Wednesday, that vaccines reduce by about 40 percent the transmission of the delta mutant that is now dominant in the world.
Its officials also stressed that vaccination, the use of masks, and social distancing remain necessary to stop the spread of infection, especially with Europe’s recent return to witnessing a new wave of high infections!